![]() Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a puzzling clinical entity that has been increasingly identified by coronary angiography during acute myocardial infarction (MI) and is characterized by clinical evidence of MI with normal or near-normal coronary arteries ( 1, 2). The GRACE risk score provides potentially valuable prognostic information on clinical outcome when applied to MINOCA patients with NSTE. ROC curve analysis showed that the GRACE risk score has moderate value in predicting MACE in NSTE-MINOCA patients. The incidence of total MACE was significantly higher in patients with high GRACE risk scores than in patients with low GRACE risk scores ( p = 0.006). There was no significant difference in non-fatal MI, stroke, heart failure, or cardiovascular-related rehospitalization. At the 1-year follow-up, the rate of cardiac death in the high risk group was significantly higher than that in the low-intermediate-risk group ( p = 0.010). Patients in the high risk group tended to be older and to have more comorbidities. The clinical characteristics and outcomes of the patients were assessed. Patients were divided into a low-intermediate risk group (≤ 140, 48.8%) and a high risk group (>140, 51.2%) according to their GRACE risk scores. We calculated the GRACE risk score for 340 consecutive MINOCA patients with NSTE. This study aimed to investigate whether the GRACE risk score is capable of predicting MACE in MINOCA patients with NSTE. The GRACE risk score is commonly used to predict major adverse cardiovascular events (MACE) in non-ST-elevation myocardial infarction patients, and the suitability of the GRACE risk score for prognostic stratification in patients with MINOCA remains uncertain. Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a special type of myocardial infarction (MI). 3Department of Cardiology, Shanghai Tenth People's Hospital Chongming Branch, Shanghai, China.2Department of Cardiology, Clinical Medical College of Shanghai Tenth People's Hospital, Nanjing Medical University, Shanghai, China.1Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.Abdu 1 † Lu Liu 1 Siling Xu 1 Bin Xu 1 Yanru Luo 1 Xian Lv 1 Rui Fan 1 Wenliang Che 1,3 *
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